Probi® Osteo

Overview

Probi® Osteo is based on a combination of three probiotic strains, Lactiplantibacillus plantarum HEAL9 (HEAL9™), Lactiplantibacillus plantarum HEAL19 and Lacticaseibacillus paracasei 8700:2 (L. paracasei 8700:2™), equally contributing to the clinically documented dose of 10 billion (10 B) CFU per day. Results from studies have shown that the combination of the three strains have an impact on bone turnover by decreasing resorption of bones. The effects of Probi® Osteo on bone health have also been investigated in early postmenopausal women.

Probi® Osteo is a registered trademark of Probi AB.

Watch the probiotic mode of action of Probi® Osteo:

Probiotic strains present in the blend/product

Lactiplantibacillus plantarum HEAL9 (HEAL9™) (DSM 15312)
Lactiplantibacillus plantarum HEAL19 (DSM 15313)
Lacticaseibacillus paracasei 8700:2 (L. paracasei 8700:2™) (DSM 13434)

Scientific reference(s)

Jansson, P.-A., et al., Probiotic treatment using a mix of three Lactobacillus strains for lumbar spine bone loss in postmenopausal women: a randomised, double-blind, placebo-controlled, multicentre trial. The Lancet Rheumatology, 2019. 1(3): p. E154-E162.

Lawenius L, Colldén H., Hustafsson K....Sjögren K., et al (2022). A probiotic mix partially protects against castration-induced bone loss in male mice. J Endocrinol, JOE-21-0408.

Ohlsson, C., et al., Probiotics protect mice from ovariectomy-induced cortical bone loss. PLoS One, 2014. 9(3): p. e92368.

Ohlsson, C., et al., Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice. Am J Physiol Endocrinol Metab, 2021. 320(3): p. E591-E597.

Lavasani S, Dzhambazov B, Nouri M, Fåk F et al. (2010). A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. PLoS one 5;2:e9009.

Additional info

Therapeutical area(s)

Healthy ageing · Women health

Functionality

Bone health · Gut permeability · Immune stimulation

Age/Gender

Adults · Elderly · Women

Dosage form

sachets, capsule, sticks

CFU/Dose

10 billion(s)

Probi® Osteo is available at

Probi AB

Probiotics, LBPs, prebiotics & postbiotics + Production & Manufacturing

Probiotic strains with Probi® Osteo

Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595)

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