Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595)


Several studies have shown that Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595) survives the passage through the GI tract, and attaches to the intestinal cells through a specific mannose-dependent binding mechanism. The bacteria can thereby exert its effects on the intestinal wall, and immune system. Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595) has also been shown to be present in the intestine up to 11 days after end of intake.

Scientific reference(s)

Olah A, Belagyi T, Issekutz A, Gamal ME and Bengmark S. (2002)Randomized clinical trial of specific lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis. British Journal of Surgery89:1103-1107. Rayes N, Hansen S, Seehofer D, Muller AR, Serke S, Bengmark Sand NeuhausP. (2002a)Early enteral supply of fiber and Lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgery. Nutrition18: 609-615. Rayes N, Seehofer D, Hansen S, Boucsein K, Muller AR, SerkeS, Bengmark S and Neuhaus P. (2002b)Early enteral supply of lactobacillus and fiber versus selective bowel decontamination: a controlled trial in liver transplant recipients. Transplantation15:123-127. KlarinB, Molin G, Jeppsson B andLarsson A. (2008) Use of the probiotic Lactobacillus plantarum 299 to reduce pathogenic bacteria in the oropharynx of intubated patients: a randomised controlled open pilot study. Crit Care12(6):R136. doi: 10.1186/cc7109. Epub 2008 Nov 6.
Adawi D, Molin G, Ahrné S and Jeppsson B. (1999)Modulation of the colonic bacterial flora affects differently bacterial translocation and liver injury in an acute liver injury model. Microb. Ecol. Health Dis.11: 47-54. Mao Y, Nobaek S, Adawi D, Molin G and Jeppsson B. (1997)Comparison of the effects of different Lactobacillusstrains in reducing bacterial translocation on Methotrexate induced enterocolitis in rats. Digest. Surg.14: 284-291. White JS, Hoper M,Parks RW, Clements WDB, Diamond T and Bengmark S. (2006)The probiotic bacterium Lactobacillus plantarum299 reduces intestinal permeability in experimental biliary obstruction. Letters in Applied Microbiology42: 19-23.

Additional info

Therapeutical area(s)

Gastrointestinal tract · Healthy ageing · Immune system


Gut permeability · Immune stimulation


Adults · Children · Elderly

Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595) is available at

Probiotic blends with Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595)

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