ProBeautyShield

ProBeautyShield is a probiotic complex by SynBalance, specifically designed to support skin health with an improvement of atopic and acneic prone skins.
It has been clinically tested in two different clinical trial targeting Atopic Dermatitis and Acne. The first randomized double-blind placebo clinical trial has involved 80 adults (40 active/ 40 placebo), with atopic dermatitis (SCORAD: 15 – 25), affected by skin dryness, desquamation, erythema and itching. Checks were scheduled at T0, T28 and T56 (end of treatment) and T84 (1-month wash-out). Instrumental and clinical parameters determined the efficacy of the treatment: subjects showed improved smoothness, skin hydration and protection, self-perception, decreased SCORAD and pro-inflammatory markers associated to AD after only 28 days, with a positive trend up to T56 and maintenance of the effect at T84. Furthermore 80 subjects (40 active/ 40 placebo), with acne severity from 1 to 3 according to IGA scale, were recruited for a second randomized placebo controlled trial and took the probiotic supplement for 8 weeks (scheduled checks at T0, T28 and T56). For ethical reasons, all subjects used a gold standard cosmetic during the trial. Results reported a significant reduction of skin sebum and pH as well as an improvement of skin moisture. Better results were collected in terms of self-perception, acneic lesions and inflammatory status. The above strains have been previously proven to colonize and persist in the GI tract after the end of treatment, thus explaining the long-term clinical effect.