Lactobacillus paracasei I 1688

Overview

Restoration of the physiological intestinal balance. Pediatric gastroenteritis. Immunomodulatory activity in allergic patients (for asthma and allergic rhinitis). Induces a significant reduction of LDL cholesterol, as well as a significant improvement of the LDL / HDL ratio. Reduces the release of type 2 cytokines, induces an improvement in the th1 / th2 ratio.

Deposited at the Laboratorium voor Microbiologie BCCM (Gent, Belgium). Deposit N°LMG P 30020.

Isolated from healthy human environment.

The microbial strain is not genetically modified and it is of natural origin (OMG Reg. (CE) 1829/2003 e 1830/2003).

Shelf life raw material: 12 months when stored below -20°C or 6 months when stored below 8°C.

Scientific reference(s)

Assessment of the persistence in the human intestinal tract of two probiotic lactobacilli Lactobacillus salivarius I 1794 and Lactobacillus paracasei I 1688 [Bonetti et al., Microbial Ecology in Health and Disease, 14:228-232, 2002].

Probiotics and children: is an integraton useful in allergic disease? [Valsecchi et al., Med. Surg. Ped, 30:197-203,2008].

“In vitro” and “in vivo” immunomodulant activity of PSMIX (Lactobacillus paracasei I 1688 and Lactobacillus salivarius I 1794). [FOCIS-Federational of Clinical Immunology Societes, Annual meeting, San Francisco 2006, doi:10.1016/j.clim.2006.04.058].

“In vitro” activation of mononuclear cells by two probiotics: Lactobacillus paracasei I 1688, Lactobacillus salivarius I 1794 and their mixture (PSMIX) [Castellazzi et al.,Immunological investigation, 36:413-421, 2007].

Assessment of efficacy of repeated administration of PSMIX and VSL3 in the model of TNBS-induced chronic colonic hypersensitivity in rats (curative paradigm) [September 2011].

Additional info

Therapeutical area(s)

Cardiometabolic · Gastrointestinal tract · Immune system

Functionality

Allergy · Anti-inflammatory activity · Cholesterol management

Age/Gender

Adults · Children

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