Lacticaseibacillus rhamnosus HA-114

Overview

L. rhamnosus HA-114 is an innovative patent-pending probiotic strain able to improve eating and mood-related behaviors in overweight adults undergoing a diet-induced weight loss. It could favor wellness and facilitate adherence during a diet-based weight reduction program, through its action on the brain-gut axis.

L. rhamnosus HA-114 supports weight management efforts during a diet (eating and stress-related behaviors, metabolic health).

The results of a recent randomized, double-blind, placebo-controlled clinical trial highlight the beneficial effects of this probiotic intervention for behavioral and psychological traits when engaging in a calorie reduced diet:

  • Eating behaviors: self-control/hunger, binge eating and food cravings, etc.
  • Mood behaviors: perceived stress and other mood-related behaviors

A healthier metabolic phenotype was also associated with probiotic supplementation.

The strain L. rhamnosus HA-114 supports weight management efforts by restoring the balance of eating behaviors through the brain-gut axis. The supplementation with L. rhamnosus HA-114 could favor wellness and facilitate adherence during a diet-based weight reduction program. The probiotic improved self-control behaviors which could lead to a better long-term adherence to dietary recommendations.

Approved health claims in Canada

L. rhamnosus HA-114 was granted the following health claims, which are the first indications of their kind in the very competitive weight management category:

  • Helps support restraint to eat in individuals involved in a weight management program.
  • Could be a complement to a healthy lifestyle that incorporates a calorie-reduced diet and regular physical activity for individuals involved in a weight management program.

Scientific reference(s)

Choi, B., et al. (2021). L. rhamnosus HA-114 improves eating and mood-related behaviors in adults with overweight during weight loss.

Additional info

Therapeutical area(s)

Gut brain Axis · Weight management

Functionality

Cholesterol management · Mood modulation

Age/Gender

Adults
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